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Dr. Monroe's serum changes H.G. while John tries to stop Utopia from leaving the island. Meanwhile, Dr. Monroe prepares for the DOD visit and gets a surprise technology windfall that he doesn't expect.
After discovering that John has traveled to 1918 to save his son, Herbert goes after him and forbids Jane from traveling with him. However, she soon discovers that the son is fated to die that day... and so, apparently, is Herbert. Meanwhile, Brooke takes steps to eliminate a man who can lead Vanessa to Project Utopia.
Back in New York in the present time, H.G. is determined to put an end to the Ripper once and for all, but John has other plans, namely to destroy H.G.'s reputation. Meanwhile, Vanessa tries to end the feud with Brooke, but Brooke has other plans.