Nue and Otoha face off, and Yurine orders Otoha to kill him. Nue's yokai friend pleads for Nue's life, and Otoha is unable to bring himself to attack Nue because he feels that Nue isn't evil. Nue flees with a bad injury. Meanwhile, Eko and his minions move their plans forward; it is revealed that Eko is using another Yurine as a power source to create his mechanised Mikura demons. Two of his minions, Tsuchigumo and Kamaitachi attack the city and Karas is forced to fight Tsuchigumo miles away from where Kamaitachi was making his move. As Karas engaged Tsuchigumi, Yurine realizes that Eko's true target was actually Otoha's human body hospitalized, "comatose" human form. Karas's fight with Kamaitachi is cut short once he sees his true body. At that point, Yurine lets her guard down and is abducted by Tsuchigumo. Without Yurine's aid, Karas loses power and disappears. Before Kamaitachi kills Otoha, Nue appears and fights with Kamaitachi, but is so weak that he can't transform into a Mikura when he runs out of bullets. Otoha awakens from his coma and kills Kamaitachi while in human form. This all was witnessed by another Karas, a young lady named En.

Eko ravages the city with a serpent-like monster powered by Nue and his brother's electricity, killing many humans. Shinjiku gathers survivors in a large room in the subway. Shinjiku, who is pushing Yoshiko in a wheelchair, meets with Kure and Sagisaka, who had come to search for his daughter. In the room, Shinjiku reveals his true Mikura form and begins eating the survivors. Shinjiku was about to attack Yoshiko, but Sagisaka sacrificed himself to save his daughter. Otoha, who had been in the group, fights Shinjiku with his sword to allow the others to escape. After surfacing, Otoha continues to fight Shinjiku but is heavily wounded when stabbed in the stomach. Otoha defends himself from a blast, he loses an arm and continues to bleed excessively. As he falls to the ground before dying, Otoha calls out for Yurine. Suddenly, white cats come running to gather around his body and transform into glowing energy, reviving Otoha. A new Yurine arises from his back and Karas returns.