Tired of being Hämsterviel's errand boy, Gantu tries to strike out on his own, losing five experiments in the school. However, Stitch is hit by both Retro and Shrink, turning him into a giant version of his old self.

While taking Yuna to school, Stitch spies someone who appears to be Lilo. Both Pleakley and Jumba are unconvinced as Lilo was starting college when they last spoke. While seeing Stitch happy with this girl, Yuna learns of how Lilo and Stitch broke up. Pleakley explains that Stitch went on a four-year mission and Lilo went to college with the promise that they would meet when they returned, but Lilo didn't. Seeing the confusion, Hämsterviel uses Morpholomew, now with the ability to transform himself into any picture the experiment sees to capture Stitch. While trying to rescue Stitch, Yuna discovers the girl Stitch has been following is actually Ani, Lilo's near-identical daughter. After stopping Gantu and capturing Morpholomew, Stitch learns that the reason Lilo didn't show up was that Lilo's sister Nani had given birth at the same time as their meeting, and the two make up after years apart.