After successful sleeve gastrectomy procedures, the Dreier twins collectively lost more than 400 lbs. and are working toward skin surgeries when a major life event disrupts their world and threatens the security they thought they had.

Ashley lost over 200 lbs. in Houston, but can she regain independence & continue to lose back in California with her enabling family? No longer a shut-in, Diana has embraced her new life and shed 300 lbs., but will knee damage threaten her progress?