Ten titans from the world of comedy and film enter the LOL house. They all are excited to prove that they can hold back their laughter for six hours. But keeping a straight face turns out to be more difficult than ever when two old acquaintances make an appearance. The record for the earliest laugh in LOL history is broken and the return of the dreaded flute puts everyone on edge.

Philippe Geubels and Jeroom Snelders will not let the participants rest and make the utmost physical demands on them. Bram struggles when his good friend enters the house. And there is even room for some unexpected romance.