The second episode picks up where the pilot left off. Andy Richter meets his adoring neighbors Phil and Teak, then finds a third man sharing the office with him and Byron. This insufferably optimistic new guy, also called Andy, starts calling Richter 'Big Andy'.

The entire office spends a weekend in Wisconsin for Ramona from accounting's wedding. Byron is out to score with a bridesmaid while Andy just wants to write. Somehow they end up in bed together.