Andy asks his friends to help him move his condescending grandmother. Before he knows it, Byron has become Andy's grandma's lover while Wendy and Keith are addicted to her old medicine. Meanwhile, Andy's neighbors Phil and Teak have fallen for Jessica.

Andy introduces Jessica to Ben, then tries to prove his theory that Ben and his twin brother are sharing her. Meanwhile, Byron has a festering burn on his back and can't change the bandages on his own.