John has endured chemotherapy and a massive operation to remove his cancer, now doctors have warned he may not survive. Also, Serina is 24 weeks pregnant, but a potentially lethal cocktail of blood types has put her unborn baby at risk.

Young chef Matthew was 18 when doctors discovered a deadly melanoma on the back of his neck. Seven years on the 25 year old is having strange hallucinations and seizures. Also, mother of four and country cop Kathleen has had to hang up her gun belt while doctors investigate a lump on her pelvis.