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When Kyle's first kidney transplant, from an organ donated by his older brother, fails, he miraculously gets a second chance at life when sister Jess offers to donate one of hers.
Tracy, a single mum of two teenagers, faces a life and death battle as her rare and aggressive brain cancer returns. We also meet Kylie, the coordinator of the RPA team revolutionising emergency stroke care.
Nurse Sharon's life is turned upside down when she is diagnosed with colorectal cancer. Putting her symptoms down to ageing, she is surprised she missed some obvious signs and faces a lengthy and complex operation to remove the cancer.