Bo and Luke accidentally pick up a crate of marijuana at the bus depot and end up on the run - But Mason Dixon, a private detective and his two sexy associates are on to the Dukes but end up working together to stop a drug-smuggling ring.

Jesse's cousin Holly Comfurt and her family suddenly strike it rich, but while in Hazzard, their car gets stolen with all of their money in the trunk. So the search is on to find the car before the thief finds the money.