After Lois reads a new book on the joys of decluttering, she challenges the rest of the Griffins to throw anything out of the house that does not spark joy. While all starts out well, Lois soon takes the decluttering to a surprising extreme.

When Brian's proposition to rename Quahog's high school "Adam West High," to honor the late Mayor West, is successful, he feels encouraged to run for office as Quahog's new mayor. The race takes a turn when Quagmire campaigns against Brian for the open seat.