When Peter makes it through a bad flu season without getting sick, the hospital asks him to volunteer as a nurse, but he finds himself at a crossroads when his mortal enemy, The Giant Chicken, is admitted to the ER. Meanwhile, Brian receives his genetic test results and learns he is part cat, causing him to have an identity crisis.

After attending a baseball game, Peter and Chris are inspired to start a memorabilia business. Meanwhile, Stewie tries to combat aging by getting plastic surgery, but ends up taking it too far.