This special half-hour FAMILY GUY tribute showcases the outrageous antics of the Griffin family and celebrates the side-splitting, irreverent humor of the fan-favorite animated series. Some of the funniest moments, satirical spoofs and musical numbers of the past 100 episodes are revisited.

While all of Quahog assumes she's dead, Lois returns from the wilderness and names Stewie as her killer, but he goes on the run while Joe leads a manhunt around Quahog. Then, Stewie tries to take over the world and in the interim auditions for the AMERICAN IDOL judges Simon Cowell, Randy Jackson and Paula Abdul. Meanwhile, Lois realizes that she must stop Stewie.