Sue and the rest of the team investigate the death of a prominent Senator's son during a college fraternity hazing. But what appears to be an open and shut case of alcohol poisoning takes a surprising turn. Meanwhile, Sue gets a lesson in instant adolescent parenting when Amanda, Sue's twelve-year-old Deaf friend, spends the week.

Continuing their investigation with a newly missing informant, the F.B.I must try and find amnesia-stricken Jonathan as his memory slowly returns, giving him more and more clues that may put an end to the case.