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Glenn questions Nancy's handling of a heroin user after a deadly batch of the drug makes it to the streets. Meanwhile, Marisa deals with an unusual theft, and Boone makes a move toward changing his future.
A plane full of holiday travelers must make an emergency landing, but things go horribly awry. Meanwhile, Nancy has reservations about seeing her family for Thanksgiving; and Boone and Tyler deal with an unusual yet typical Thanksgiving emergency.
A construction worker becomes trapped underground after stumbling down a manhole, and Nancy's phobia hinders his treatment. Elsewhere, Rabbit and Marisa care for victims of a bank robbery; and Boone makes a critical decision in his new position that threatens a coworker's career.