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Grace to is forced to confront her own past trauma when she encounters a patient whose diagnosis proves to be elusive.
Wolf is assigned to a patient that has lost hope that she will receive a life-saving lung transplant in time; Keon confides in a former football friend about a traumatic incident; Naz is assigned as Sinead's assistant
Grace mediates between a patient's partner and son while adjusting to the unwanted arrival of the new hospital CEO.
Nurses follows four young nurses working on the frontlines of St. Jude's hospital dedicating their lives to helping others, while figuring out how to help themselves.