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An Amber Alert rings out at St. Mary's, but unbeknownst to the nurses the perpetrator and the abducted child are in the hospital.
A hospital is a battlefield as five nurses attack another season with a new general in town: nurse manager Kate Faulkner, who will give them all a run for their money.
Hospitals are no stranger to the things that keep us up at night or the secrets we keep, as the strange gets stranger on the night shift at St Mary's.