Sponsored by ING Group, the competition was the fifth World Marathon Major of 2010 and an IAAF Gold Label Road Race.[1] A record 45,344 people were entered into the race. Ethiopian runner Gebregziabher Gebremariam won the men's race in a time of two hours, eight minutes and fourteen seconds on his debut performance over the distance.[2] Edna Kiplagat of Kenya took first place in the women's race with her winning time of 2:28:20.

In the wheelchair races, Great Britain's David Weir (1:37:29) and America's Tatyana McFadden (2:02:22) won the men's and women's divisions, respectively. In the handcycle race, Americans Dane Pilon (1:21:23) and Helene Hines (2:02:16) were the winners.