Dennis has several giant growths on the back of his head. Juan has a rare condition he hopes Dr. Lee will understand. Natalie searches for answers as to why her body is covered in hundreds of mysterious dark bumps.

John fears the large lump on his neck could become so big that it may eventually suffocate him; Shoshana is depressed because of the big growth on her forehead; Ashley hopes Dr. Lee can provide some relief from her three painful skin conditions.