Robert has thousands of unique bumps on his arms that Dr. Lee has never seen. Alexis has a painful cheek cyst that oozes and has a pungent odour. Stuart's cluster of back bumps disgusts his wife, but thrills Dr. Lee.

Elizabeth's head is covered with giant cauliflower-shaped bumps. Jamaal has been growing a strange knob on the left side of his butt since he was just a boy. Donna's cracking, bleeding skin condition has aged her face and kept her from being social.