In their battle against the cartels, Customs and Border Protection flag a tractor-trailer transporting tanks of liquid methamphetamine; officers nab an exotic reptile smuggler; 36 pounds of cocaine are found inside a pickup truck.

Officers in Laredo, Texas, help a troubled 14-year-old; drugs sent through the mail are seized; a nurse in Progreso, Mexico, is caught smuggling fentanyl; a woman with children is stopped; a drunken woman bares all to officers.