A man returning from Mexico requires emergency Narcan at the border after a suspected opioid overdose. An odd family gets apprehended while attempting to sneak weapons into Mexico. A woman caught red-handed attempting to smuggle prescription medications into the United States. 

Couriers heading south are carrying a surprise shipment of supplies for narcotics distribution; a man who didn't realize he had a warrant for his arrest is apprehended, and officers get creative when bricks of narcotics are found hidden deep within a semi.