In 1994, Justice Horace Krever is appointed to lead an inquiry into the tainted blood scandal. Shocking revelations and heart wrenching testimony are laid bare as he digs for the truth. Estranged from his family, Ben's quest for revenge is galvanized, as victims around him continue to die. Krever is halted when those he intends to accuse of misconduct take him to court.

As the criminal trial falls apart, Ben considers taking matters into his own hands. Peter and Ryan both struggle with illness while forging families of their own. In 2015, both of their lives hang in the balance as the tragedy finally threatens to catch up to them.