Jeppe and Regitze are divorced and have different ways of coping with life. Jeppe tries to get a handle on the anger through mindful yoga, and Regitze fixes the guilt with dry cleaning and AA meetings. Bo still sits as 2nd clarinet in the Orchestra, while his former student Elin is firmly planted in the first seat. But Elin is heavily pregnant, so the first seat will soon be free. As acting boss, Jeppe must solve the Gordian knot of filling the hall with a new and preferably younger audience.

Jeppe tries to appeal to the young audience and has invited the female rapper Sin The Rellah as a guest artist together with the Orchestra. They have to perform Let them burn - Rellah's most popular number, and Alma is super excited. Vibeke is placed against her will in a nursing home in Herlev, where she will live for the last time, and Bo tries to make it cozy, while he has to accept with disgust that Simon is back as 1st clarinet.