The kingdom has been infiltrated by a girl named Ren from the Assassin's Guild.. Upon learning of her special ability as the Poison Blighted, Lloyd tracks her back to her hideout, sneaks in, and is attacked by a group of assassins with unique abilities.

Ren is confronted by the demon lord Guisarme, who has stolen Jade's body and teleportation power. Guisarme is intent on seizing the bodies of the Assassin's Guild as well, when Lloyd arrives in the neck of time to defend them.