Isa breaks with Wayne over the recent bloodshed and engages in risky behavior, both professional and personally. Wayne visits a figure from his past, and in flashback, we learn the tragic origins of his hatred for Bautista. Bautista takes a physical and spiritual journey into the hills of Guerrero, coming to a decision that will have horrible consequences for Lalo and the entire country of Mexico.

Lalo has a head-to-head confrontation with the Guerrero cartel, with fatal results. A risky Hail Mary from Wayne puts him and Isa into bloody conflict with the Northern Federation. And Isa and Lalo come to a realization about their relationship.