Suffering from a degenerative disease, Benji has been in hospital for years. His best friend, Gabriel, is in a wheelchair following a terrible car accident. They will meet Zoé, admitted for an arm fracture, but whose analyses reveal that her state of health is more serious than expected. Forced to stay in the hospital as she prepares to take her entrance exams in Oxford, Zoé shares her room with Emma. She is waiting for her mother's analysis results to obtain a kidney transplant. Finally, Nathan is admitted to the emergency room, victim of a surfing accident. Gabriel will have to share his room with someone he would have liked to never see again...

Lors de son traitement, Zoé rencontre César, qui se bat contre son cancer depuis des années et lui explique que la chimio peut faire baisser les capacités intellectuelles… Zoé réalise alors qu'elle doit abandonner son concours pour se traiter. Quant à Gabriel, il avoue à Benji la vraie raison de son accident. Et Nathan n'y est pas étranger. Autre mauvaise nouvelle : la transplantation d'Emma ne s'est pas passée comme prévu. Son dernier espoir : retrouver ce père qu'elle n'a jamais connu.