A two-year-old Labrador's life is on the line. Willow has been rushed to the hospital as an emergency because a severe infection has taken hold in her chest, leaving her struggling to breathe. Graeme is invited into surgery as the soft tissue team operate on Willow to relieve the pressure on her lungs and heart before trying to find the cause of the infection. For 24 critical hours, distraught owners Charlie and Amanda desperately hope their beloved companion pulls through.

Graeme meets Miniature Dachshund Dotty and her owner Olivia who are inseparable. They literally do everything together. Dotty has developed an immune disorder which has caused blindness in her right eye. The hospital has advised Olivia that her precious best friend needs an urgent procedure to remove the blind eye - a life-changing operation. But the ophthalmology team are concerned that Dotty's left eye is also showing signs of inflammation caused by the immune condition. Will they be able to do anything to save Dotty's left eye to avoid total blindness?

Nine-year-old Golden Retriever Millie lives with her sister Chloe and owner Bethan. The three girls are at their happiest when enjoying adventures together in Bethan's campervan. Millie has been referred to the hospital with an unexplained mass in her chest. Sadly, Bethan receives the news she has been dreading, that her beloved Millie has cancer. Graeme finds out from the specialists whether the tumour can safely be treated with modern technology, in the hope that Millie and Bethan are able to get away for more travels to spend precious time together.

Graeme Hall meets a five-year-old Dachshund who needs life-changing spinal surgery to give him the chance to get back on his feet. Vader has become very unsteady on his back legs. Owners Amber and Dan face a tough decision – if left without an operation, their beloved companion could lose the ability to walk, but equally the operation is high risk which could leave Vader paralysed.

Daisy, an eight-year-old Chocolate Labrador, requires major surgery on a back leg after suffering a nasty accident while chasing a cat. A visit to the hospital reveals Daisy needs a complex procedure to replace a diseased Achilles tendon. Graeme joins Orthopaedic Specialist Alexis Bilmont in the operating theatre where an unexpected complication leaves Daisy requiring further surgery. It's an anxious time for owners Michelle and Gary.

Eight-year-old Bassett Hound Lottie has been battling cancer for over 12 months. Lottie's family had already suffered a tragic loss, so her illness has been all the more challenging for Mum Beccy and her children Jamie and Emily. Graeme sees at first hand the incredible work carried out by the hospital's Oncology team who help brave dogs like Lottie fight cancer. A course of chemotherapy could be her best chance of survival. Will the treatment prove a success leaving her cancer free?