Dr Caitriona is put under pressure to insert a cannula into an elderly patient in desperate need of intravenous medication to save her life. On his first day in Children's ED, Dr Javed is way out of his comfort zone.

Dr Eoin is searching for answers and stronger painkillers when a 57-year-old woman presents to ED with excruciating chest pain. Dr Natalie is concerned her 76-year-old patient, brought in by ambulance, is suffering from a life-threatening blood clot.