Mignon Francois, founder and CEO of The Cupcake Collection; 79-year-old vet Kenny Jary turns a viral moment into help for others; a woman loses over 200 pounds; a man rediscovers his passion for painting after Parkinson's disease diagnosis.

A look back at 2021; getting glamorous for New Year's with Zanna Roberts Rassi; creating one's vision with Maria Shriver; what to watch in 2022.