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Posing as a watchmaker who manufactures bomb timers, MacGyver manages to catch a master killer—Piedra—before he attempts an assassination on a high-profile target. However, Piedra isn't about to be stopped for long.
Pete is made to believe that his Russian friend, Alexander Kharsov, is dead. When he realizes he's alive and being held in a mental hospital, he enlists MacGyver's help. Helped by Mariah, Alexander's daughter, they will try to get him out of there before he is killed.