When MacGyver is sent to rescue an American pilot held in Central America for supposed espionage, his wargame-trained daughter tags along, but she didn't quite come prepared for the real thing. MacGyver must now rescue the pilot while keeping his daughter safe from the soldiers.

MacGyver is called to a meeting with a former British spy, who has learned of a group of terrorists that will use a new plastic explosive in a vengeful attack on the U.S. army. This explosive can be hidden anywhere. However, before the spy can give MacGyver all the details he is shot. MacGyver flees through a window and is picked up by a boat. The female who owns the boat soon learns that the man she has rescued doesn't have any memory.