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Jack Dalton is brainwashed by an African politician and his wife to assassinate the leader of an African nation, who is in town for an awards ceremony.
MacGyver heads up a trip with four other Phoenix Foundation employees into the wilderness as part of a stress reduction program. After discovering that a prison bus accident has freed several prisoners, the employees begin to question each other's behavior. MacGyver must now figure out which man, if any, is not to be trusted before it's too late.
MacGyver and Pete are captured by terrorists intent on wiping out a nearby city with an electromagnetic pulse, unless their leader is freed.