There is big party to celebrate Caroline's 2000th cartoon strip. However, Caroline has a mental block and is unable to draw anything. Her friends give her plenty of bad suggestions, so she contemplates retirement and trying something else.

Caroline has to make a quick return home. Her parents have moved house but her grandmother is staying put and doesn't want to move out. This leaves Richard in charge of a sick Annie and a depressed Del, and having to make a speech.