Acclaimed actors Colman Domingo, Robert Downey Jr., Paul Giamatti, Mark Ruffalo, Andrew Scott and Jeffrey Wright on their first big breaks, the person they'd most want to work with and what they'd be doing if they weren't actors.

Six comedy actresses tell stories from set: Quinta Brunson, (Abbott Elementary), Michelle Buteau, (Survival of the Thickest), Renee Elise Goldsberry, (Girls5Eva), Ego Nwodim, (Saturday Night Live), Maya Rudolph, (Loot), Kristen Wiig, (Palm Royale).