Daddy Farquhar continues to visit the Clampetts's mansion to his daughter Margaret's displeasure. He has plans for Granny and her money in Las Vegas but she's expecting a marriage proposal.

When Mr. Drysdale is unhappy with Dr. Clyburn's treatment of his cold the Clampetts hear about it. Granny decides it's time to set up practice and enlists the rest of her family to help. She also claims a cure for the common cold.