James "Ghost" St. Patrick forms a dangerous alliance with his brother-in-arms, Tommy, and mortal enemy Kanan. Angela is implicated in murder and turns to an unlikely ally. Tasha enlists LaKeisha to protect Tariq.

Ghost and Tasha butt heads on how to grieve; Angela pursues the Jimenez Cartel while Kanan goes after Dre's organization; Tommy confides in LaKeisha about his relationship with Teresi, complicating everyone's lives.