In the Season 2 premiere, Mary Jane throws a dinner party; and invites a married couple whom she and David used to be "couples friends" with. She also re-examines what she wants out of life after learning that David's new girlfriend is pregnant.

Mary Jane undergoes a fertility treatment as part of a series on modern-day motherhood. She also makes Niecy her new pet project after Niecy's secret is discovered; and tries to land an interview with an elusive multi-millionaire.