Mary Jane undergoes a fertility treatment as part of a series on modern-day motherhood. She also makes Niecy her new pet project after Niecy's secret is discovered; and tries to land an interview with an elusive multi-millionaire.

Kara suggests a live installment of "Talk Back," but neither she nor Mary Jane are prepared for the news that Dr. Marrs delivers; Cameron and Niecy negotiate over his re-entry into her life; and an exciting business opportunity presents itself to PJ.