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John F. Kennedy's doctor administers him meth for his back pain; Dr. John C. Lilly takes LSD while studying the intelligence of dolphins.
People going to extremes for love, including a student who tunnels beneath the Berlin Wall, Edie Windsor topples the Defense of Marriage Act, and John Wojtowicz robs a bank to pay for his wife's gender reassignment surgery.
Journalist Maurine Dallas Watkins writes a play about Chicago's infamous Murderesses' Row; Mata Hari goes from exotic dancer to double agent during World War I.