Popular high school teacher is killed in a hit and run that is clearly no accident. The squad works to solve the case, but Jane is preoccupied with Lt. Martinez's apparent favoritism towards his own drug unit.

When Jane and Maura are asked to present the case of serial killer Charles Hoyt at a symposium for law enforcement, Jane worries that her greatest challenge will be facing bad memories. However, as she and Maura begin a simulation of investigating Hoyt's murders, they soon come across a horrifying discovery. In a matter of moments, the team finds themselves drawn into a lethal game of cat and mouse with a new and terrifying serial killer.