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The clock is ticking as the team works to solve a murder with explosive consequences. Angela balks when Ron offers to take her on a romantic getaway.
When a gun battle rages in a quiet neighborhood, leaving one dead, Jane and Maura are thrown into the secretive world of an Eastern European gang. Maura comes down with a fever while juggling work and play, and Angela and Kent prescribe several home-remedies that have a surprising effect.
When a State Trooper is killed in Maine, the getaway car is traced back to the mastermind of the attacks on Jane. The team must now unravel the mystery of the mastermind's obsession with Jane in order to keep her safe and turn the hunter into the hunted. Meanwhile, Korsak prepares to tie the knot with Kiki.
Hit drama Rizzoli & Isles returns for season six with stars Angie Harmon and Sasha Alexander as Boston's top crime-solving duo. Idara Victor joins the cast as a series regular this season as crime scene analyst Nina Holiday, and Adam Sinclair (24: Live Another Day) will have a recurring role as Kent Drake, an assistant medical examiner in Maura's office.