The LAPD flies a material witness into Los Angeles to testify, but in a horrible turn of events their witness winds up as the key suspect in an entirely new murder. Personal and professional stress takes a toll on Flynn. And the squad takes bets when Rusty brings a girl from class to hang out with him at the department.

When a child with gender dysphoria goes missing, the Major Crimes division scrambles to solve the emotional case before it's too late. Torn between several suspects, the squad has to be careful as it tries to connect the evidence to a dangerous bully. Meanwhile, Jack Raydor attempts to make up for years of lousy parenting.