Drug lord Alonso Marroquín is about to be extradited to the US, but an elite police unit, the DEA, the corrupt prison warden and a rival cartel all have other plans for him. Across the border, on a secret US military base, a secret experiment yields an unexpectedly dangerous result.

Snowman's plans to expand his experiments take an unexpected turn. Despite being fired and threatened, Lilia decides to keep going and interview the world's most wanted fugitive. DEA agent Taft breaks the chain of command and sets out on a personal quest. Meanwhile, Lucas disobeys his father's orders.