A strange parasite invades Pete's body and feeds on the teen's adrenal glands, causing him to shake off his inhibitions and engage in wild and dangerous behavior. Meanwhile, Clark gathers his courage and asks Lana for a date, which she eagerly accepts.

Martha is hospitalized after becoming seriously ill from exposure to kryptonite spores in the Kent's storm cellar, and Jonathan learns there are complications. Meanwhile, Lex's girlfriend is offered a lucrative position at a hospital far away from Smallville.