When two cheerleaders develop a love potion that arouses feelings of extreme devotion and jealousy, it causes a football player to attack Jason for "checking out" his girlfriend and prompts Chloe to hit on Clark. Also: Clark is made starting quarterback, a promotion that doesn't sit well with his new teammates; and Lex donates new uniforms to the team, but Clark is put off by the gesture, which he takes as an attempt to buy back his friendship.

Clark switches bodies with Lionel after Clark interferes with the exchange of a Kryptonian stone that was meant for an unsuspecting Lex. Consequently, Clark takes Lionel's place in prison, while Lionel takes advantage of his newfound freedom---and superhuman abilities.