The stage is set for a clash of the Titans when Gabrielle inadvertently releases three of the giant deities from a centuries-long entombment and one of them proceeds to terrorize a village—against the wishes of the other two.

Hades, god of the underworld, asks Xena to undertake the daunting task of freeing his sister—the embodiment of death—from the clutches of a greedy king who's captured her.