The Angels go undercover in the fashion world after a young model's disappearance, and Kate's ex-fiance, Detective Ray Goodson, is involved with the case.

Based on a teleplay from the original "Charlie's Angels" series, the girls must break out of jail in their quest to crack a case. This time, they pose as unsuspecting American tourists to crack a kidnapping ring in Cuba. Upon arrival at the hotel, they are framed and thrown into a women's prison, where their key victim, Tess, is also incarcerated. Bosley joins forces with his ex-girlfriend, CIA operative Samantha Masters, but is this partnership something more?