Kabuto's past is finally revealed. As child, a woman named Nonou raised Kabuto at an orphanage in the Leaf Village. One day, Danzo and Orochimaru visit the orphanage to provide financial aid under the condition that Nonou work as their spy.

Itachi activates the Visual Jutsu Izanami to trap Kabuto's mind. Itachi then explains to Sasuke how Izanami was originally developed to keep the Uchiha from abusing the power of Izanagi.