While pursuing Orochimaru, Kakashi wanders into a village inhabited by the Iburi Clan, a group of people with the unique ability to turn into smoke. Kakashi is soon captured and learns that the villagers all serve under Orochimaru.

Danzo orders Tenzo to kill Kakashi and take his Sharingan. Reluctant at first, Tenzo decides to carry out his orders after learning that the Leaf Shinobi has come to be known as "Kakashi the Friend Killer."